@article { author = {Rostami, Zohreh and Rouhanizadeh, Masoumeh and Nami, Navabeh and Zareyee, Daryoush}, title = {Fe3O4 magnetic nanoparticles (MNPs) as an effective catalyst for synthesis of indole derivatives}, journal = {Nanochemistry Research}, volume = {3}, number = {2}, pages = {142-148}, year = {2018}, publisher = {Iranian Chemical Society}, issn = {2538-4279}, eissn = {2423-818X}, doi = {10.22036/ncr.2018.02.003}, abstract = {The principal aim of this research is the application of Fe3O4 (MNPs) in the synthesis of some indole derivatives. Fe3O4 MNPs were prepared by Co-Precipitation method from the reaction of FeCl2.4H2O and FeCl3.6H2O in ammonia solution. Morphology and structure of Fe3O4 MNPs were determined by FT-IR, X-Ray diffraction (XRD), transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Fe3O4 (MNPs) has been used as a highly efficient catalyst for the synthesis of some Indole derivatives like 6H-Indole [2,3-b] quinoxaline, 3-methyl–6H-Indole [2,3-b] quinoxaline and (z)-3-(pyridine-2-yl-imino)-Indole-2-one. The reaction was carried out using various amounts of Fe3O4 nanoparticles in various solvents and solvent-free conditions. The optimum amount of nano-Fe3O4 was 5 mol% in THF under reflux conditions. The structures of indole derivatives were further established by NMR, and FT-IR spectra. In view of excellent catalytic capacity, the exceedingly simple workup procedure, environmentally friendly reaction and good yield, Fe3O4 (MNPs) was proved to be the good catalyst for this reaction.}, keywords = {Fe3O4 magnetic nanoparticles,Indole derivative,Green chemistry,easily separation}, url = {http://www.nanochemres.org/article_81104.html}, eprint = {http://www.nanochemres.org/article_81104_da6b249868edca2c2fc13572fb87b922.pdf} }