%0 Journal Article %T Fe3O4 magnetic nanoparticles (MNPs) as an effective catalyst for synthesis of indole derivatives %J Nanochemistry Research %I Iranian Chemical Society %Z 2538-4279 %A Rostami, Zohreh %A Rouhanizadeh, Masoumeh %A Nami, Navabeh %A Zareyee, Daryoush %D 2018 %\ 12/01/2018 %V 3 %N 2 %P 142-148 %! Fe3O4 magnetic nanoparticles (MNPs) as an effective catalyst for synthesis of indole derivatives %K Fe3O4 magnetic nanoparticles %K Indole derivative %K Green chemistry %K easily separation %R 10.22036/ncr.2018.02.003 %X The principal aim of this research is the application of Fe3O4 (MNPs) in the synthesis of some indole derivatives. Fe3O4 MNPs were prepared by Co-Precipitation method from the reaction of FeCl2.4H2O and FeCl3.6H2O in ammonia solution. Morphology and structure of Fe3O4 MNPs were determined by FT-IR, X-Ray diffraction (XRD), transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Fe3O4 (MNPs) has been used as a highly efficient catalyst for the synthesis of some Indole derivatives like 6H-Indole [2,3-b] quinoxaline, 3-methyl–6H-Indole [2,3-b] quinoxaline and (z)-3-(pyridine-2-yl-imino)-Indole-2-one. The reaction was carried out using various amounts of Fe3O4 nanoparticles in various solvents and solvent-free conditions. The optimum amount of nano-Fe3O4 was 5 mol% in THF under reflux conditions. The structures of indole derivatives were further established by NMR, and FT-IR spectra. In view of excellent catalytic capacity, the exceedingly simple workup procedure, environmentally friendly reaction and good yield, Fe3O4 (MNPs) was proved to be the good catalyst for this reaction. %U http://www.nanochemres.org/article_81104_da6b249868edca2c2fc13572fb87b922.pdf